Grilinctus-L

⚙️ Composition & Mechanism

Active Ingredient: Levocloperastine 20 mg per 5 mL — a non‑opioid antitussive that suppresses dry cough by reducing the activity of brain’s cough center .

Some sources mention a combination with chlorpheniramine, though the standard Grilinctus‑L formula (by Franco‑Indian Pharmaceuticals) is monotherapy with levocloperastine .

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✅ Indications

Primarily prescribed for non‑productive/dry cough, including those due to:

Viral infections (like cold or flu)

Bronchitis

Allergic coughs and post‑viral cough syndrome .

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💊 Dosage & Administration

Adults & elderly: typically 5 mL up to 3 times daily .

Children (2–12 years): smaller doses—e.g., 2 mL twice daily (2–4 yrs) or 3 mL twice daily (4–7 yrs) .

Take with or without food, but maintain consistent timing daily.

Use the measuring device (not a household spoon), shake well before use .

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🧪 Pharmacodynamics

Levocloperastine blocks both the central cough center and peripheral cough receptors, relieving the urge to cough .

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⚠️ Side Effects

Common mild-to-moderate side effects include:

Nausea, dry mouth, dizziness, drowsiness, headache, fatigue, palpitations, fainting, gastrointestinal upset, confusion, numbness .
Most are temporary; consult a doctor if persistent or severe.

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🚫 Warnings & Precautions

Avoid alcohol: may increase drowsiness .

Driving/machinery: avoid if experiencing dizziness or drowsiness .

Pregnancy/lactation: insufficient safety data—use only if prescribed .

Renal/hepatic impairment: use with caution; physician supervision required .

Children: not recommended under 2 years; caution advised for those under 8 years .

Elderly: dose adjustments as they may be more susceptible to side effects .

Comorbidities: caution for patients with heart disease, diabetes, hyperthyroidism, seizures .

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🔄 Interactions

Caution with other CNS depressants (e.g., antidepressants, antihistamines, sedatives): may enhance drowsiness .

Disease states: may require close monitoring or dose changes in hyperthyroidism, diabetes .

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⏱️ Course of Treatment

Begin relieving cough within ~15 minutes of dose in most cases .

Usually prescribed for up to 7 days—consult a doctor if symptoms persist beyond that or in case of fever, rash, or headache .

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💾 Storage & Packaging

Supplied in 100 mL bottles.

Store below 30 °C, keep dry and away from direct sunlight, out of children’s reach .

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💡 Quick Tips

Use a proper measuring cup; do not double doses after a missed one .

Stay hydrated to ease cough .

Avoid if cough becomes productive (with phlegm) or lasts beyond 7 days without improvement .

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💰 Pricing & Substitutes

MRP ~₹125–156 per 100 mL bottle (varies by platform) .

Several alternatives include Lupituss-L, Phensedyl LR, Soventus‑DC, and Zerotuss .

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ℹ️ Summary Table

Feature Details

Composition Levocloperastine 20 mg/5 mL
Use Dry cough suppression
Dose Adults: 5 mL 3×/day; adjust for children
Onset ~15 minutes
Max. Duration ~7 days (seek medical advice beyond this)
Storage Below 30 °C
Side Effects Nausea, drowsiness, dizziness, etc.
Caution Alcohol, driving, pregnancy, elderly, comorbidities

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🩺 IMPORTANT

This information is educational. Always follow your prescribing doctor’s instructions, and consult them before using. Seek immediate medical help if you experience serious reactions like severe dizziness, palpitations, or allergic symptoms.

Let me know if you’d like reminders, comparisons with other syrups, or usage during pregnancy, and I can find that info too!