Grilinctus-DX

Composition & What It Treats

Active Ingredients (per 5 ml):

Chlorpheniramine maleate – antihistamine (2 mg)

Dextromethorphan hydrobromide – cough suppressant (10 mg)

Primary Uses:

Suppression of dry, non-productive cough

Relief from allergy-related symptoms (e.g. sneezing, runny nose, throat irritation)

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⚙️ How It Works

Dextromethorphan depresses the brain’s cough center, reducing coughing reflex

Chlorpheniramine blocks histamine, alleviating allergy symptoms like sneezing and runny nose

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👶 Dosage Guidelines (Typical)

Adults & adolescents (13 + years): 5–10 ml every 6 hours, up to 7 days

Children 2–12 years: Usually half the adult dose (e.g. 5 ml every 6 hours), but only if prescribed by a doctor

Note: Use exactly as directed; do not exceed recommended dose—overdose can lead to respiratory depression, coma, seizures

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⚠️ Common Side Effects

Drowsiness, sedation, dizziness, blurred vision, dry mouth, constipation

Stomach upset, nausea, headache, abdominal discomfort, fatigue

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🚨 Serious Risks & Precautions

Overdose may cause dangerously slow breathing, pale/blue lips, seizures, coma—seek immediate medical help

Avoid using with MAO inhibitors or serotonergic drugs (e.g., phenelzine, selegiline, SSRIs) due to the risk of serotonin syndrome

Not recommended (or used with caution) in:

Children under 2 years

Patients with asthma, COPD, chronic bronchitis

Those with glaucoma, enlarged prostate, urinary retention, or phenylketonuria, fructose intolerance

Use caution if pregnant, breastfeeding, or having liver/kidney disease

Avoid alcohol—can worsen drowsiness and sedation

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🕒 When & How to Use

1. Shake well before dosing.

2. Can be taken with or without food, but maintain consistency.

3. Use measuring cup for accurate dosing.

4. Do not drive or operate machinery if affected.

5. Drink plenty of fluids to help soothe throat and hydration

6. Finish full course unless a doctor advises otherwise—don’t stop early or increase dose. If symptoms linger longer than 7 days or worsen (e.g. fever, rash, headache), consult a doctor

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💊 Drug Interactions

Serious with MAO inhibitors (e.g., linezolid, phenelzine, selegiline, rasagiline): risk of serotonin syndrome

Can interact with SSRIs, antipsychotics → increased drowsiness or other side effects

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💡 Storage

Store in a cool, dry place away from direct sunlight, preferably below 30 °C. Keep out of reach of children

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✅ Summary Table

Aspect Details

Composition Chlorpheniramine 2 mg + Dextromethorphan 10 mg per 5 ml
Use Dry cough & allergy relief
Adult dose 5–10 ml every 6 h (max ~40 ml/day)
Kids (2–12 yrs) ~5 ml every 6 h if prescribed
Side effects Drowsiness, dizziness, dry mouth, GI upset, headache
Serious risks Respiratory depression at high doses; drug interactions
Precautions Avoid in specific conditions; caution for pregnant/breastfeeding/liver
Interactions MAOIs, SSRIs, sedatives, alcohol
Storage Room temp (<30 °C), away from light

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Important: Always use under medical supervision. If symptoms worsen or side effects persist, stop using it and consult a healthcare provider.