Itromed 200 Capsule

What It Is & Mechanism of Action

• Generics of itraconazole, an oral azole antifungal that inhibits ergosterol synthesis, disrupting fungal cell membranes

• Used to treat a range of fungal infections including skin, nail, oral, esophageal, pulmonary, and systemic (e.g. blastomycosis, histoplasmosis, aspergillosis)

Indications

Prescribed for fungal infections such as:

• Onychomycosis (nails), skin (tinea), mouth/throat (oral/esophageal candidiasis), lungs, and internal organs

Dosage & Administration

• Strength: 200 mg capsule.

• Directions: Typically taken once or twice daily with food to enhance absorption

• Duration: Depends on the infection—ranging from a few weeks (skin) to months (nails/systemic).

• Swallow whole; do not crush or chew

• Finish the full prescribed course to avoid recurrence or resistance

Side Effects

Common (usually mild):

• Nausea, vomiting, diarrhea, stomach pain, headache, dizziness, fatigue

Serious:

• Liver toxicity (monitor enzymes), congestive heart failure risk, QT prolongation, visual/hearing changes, allergic reactions

• Peripheral neuropathy (numbness or tingling reported).

Precautions & Warnings

• Heart conditions: Avoid if you have congestive heart failure

• Liver/kidney disease: Use cautiously; may require monitoring and dose adjustment

• Pregnancy/Breastfeeding: Not recommended during pregnancy, especially 1st trimester; use contraception and avoid if breastfeeding unless essential

• Blurry vision/dizziness: Avoid driving/heavy machinery if affected

Drug & Food Interactions

• Antacids / PPIs / H₂-blockers: Take at least 2 hours apart—acidic stomach improves absorption

• CYP3A4 substrates: Avoid or monitor use with statins, benzodiazepines, anticonvulsants, anticoagulants, antiretrovirals, quinidine, cisapride, pimozide

• Grapefruit: May increase blood levels—avoid

• Alcohol: Avoid or limit due to possible increased side effects

Packaging & Cost (India)

• Commonly sold in strips of 4 or 10 capsules; a 10‑capsule strip costs around ₹135–₹150 (≈₹14–15 per capsule) on e-pharmacies like PharmEasy

• Store in a cool, dry place below 25–30 °C and keep out of reach of children

Summary Table