Cefixime & Ofloxacin Tablets 200mg 1*10

Indications (Uses):

Respiratory Tract Infections (such as pneumonia, bronchitis, and sinusitis)

Urinary Tract Infections (UTIs)

Otitis Media (ear infections)

Gonorrhea (a sexually transmitted infection)

Pharyngitis and Tonsillitis (infections of the throat)

Typhoid Fever (caused by Salmonella bacteria)

Dosage: For adults, the usual dose is 200 mg once daily or 100 mg twice daily, depending on the infection. For children, the dosage varies based on weight and the specific infection.

Side Effects: Common side effects include diarrhea, nausea, abdominal pain, rash, and headache. Severe allergic reactions, like anaphylaxis, are rare but possible.

Precautions:

Use with caution in patients with a history of gastrointestinal disease, particularly colitis.

If you are allergic to penicillin, there may be cross-reactivity.

Cefixime should be used with caution in patients with kidney problems.

2. Ofloxacin:

Class: Ofloxacin is a fluoroquinolone antibiotic.

Mechanism of Action: It works by inhibiting bacterial DNA gyrase, which is essential for DNA replication and cell division in bacteria.

Indications (Uses):

Respiratory Tract Infections (like pneumonia and bronchitis)

Urinary Tract Infections (UTIs), including cystitis and pyelonephritis

Skin and Soft Tissue Infections

Gastrointestinal Infections

Ophthalmic Infections (eye infections, when used in eye drop form)

Sexually Transmitted Infections like chlamydia and gonorrhea

Prostatitis (infection of the prostate gland)

Dosage: Ofloxacin is usually taken 200–400 mg once or twice a day. The dosage can depend on the type of infection being treated.

Side Effects: Some common side effects include dizziness, nausea, headache, sleep disturbances, and gastrointestinal issues (like diarrhea). Serious side effects include tendonitis, tendon rupture (rare), and central nervous system effects like confusion, seizures, or hallucinations.

Precautions:

Ofloxacin should be used with caution in patients with a history of seizures or those taking medications that lower the seizure threshold.

Not recommended during pregnancy, unless absolutely necessary, as it can affect fetal development.

May increase the risk of tendon rupture, particularly in older adults or those on corticosteroid therapy.

Alcohol should be avoided as it can worsen side effects like dizziness or lightheadedness.

Combination of Cefixime and Ofloxacin (200 mg Tablets):

In some cases, both of these antibiotics may be prescribed together, especially if the infection is caused by multiple types of bacteria, or if the bacteria are resistant to certain classes of antibiotics.

Indications for Combination:

Severe or complicated infections (e.g., mixed infections of the respiratory or urinary tract)

Treatment of infections caused by both Gram-positive and Gram-negative bacteria.

Gonorrhea and other STIs when caused by multi-drug-resistant bacteria.

Precautions:

Since both are antibiotics, it’s important to complete the entire prescribed course even if symptoms improve early.

The combination may increase the risk of certain side effects, especially gastrointestinal problems or allergic reactions.

Would you like more details on specific interactions, or a breakdown of side effects for each medication?